Certain ways you would need to know to get the best Widal Test Center in Mumbai. The Widal test measures the ability of antibodies against LPS and flagella in the serum of people suspected of having typhoid fever to agglutinate S. Typhi cells; it was first used over a century ago and is still widely used today. It’s easy to do, cheap, and only takes a few minutes. A positive result is indicated by a four-fold increase in antibody titer in an acute and convalescent-phase serum sample taken about 10 days apart.
In practice, however, only one acute-phase serum sample is typically used, which can lead to confusion. Because other Enterobacteriaceae and diseases such as malaria can produce antigenic determinants that cross-react with S. Typhi, it is preferable to use the first test to establish a baseline titer and then look for an increase in the second test.
Although ELISA-based studies against the same antigens are more sensitive than agglutination tests, they share the Widal test’s limitations in terms of specificity. Antibodies to the Vi antigen usually appear too late in the illness to be useful for diagnosis, but the Vi antigen has been proposed as a way to detect chronic carriers.
Purpose of the test
The purpose of this Widal Test Center in Mumbai is to check the levels of certain antibodies in the blood. Antibody titers are the measurements of these levels. Titers above a certain threshold indicate that the immune system has been exposed to a vaccine or a pathogen previously.
